What is the most significant bit and the least significant bit in a binary code ?

In a binary code, the leftmost bit is called the most significant bit or MSB. It carries the largest weight. The rightmost bit is called the least significant bit or LSB. It carries the smallest weight. For example:

$\begin{matrix} \underset{\bold{MSB}}{1} & 0 & 1 & 1 & 0 & 1 & 1 & \underset{\bold{LSB}}{0} \end{matrix}$